Kaansarii Kalee (RCC)
🧠 Kaansarii Kalee (RCC)
- Kansarii hamaa seelota ujummoo kalee (renal tubular epithelium) irraa maddun dha.
- Gosa kaansarii kalee ga’eessota keessatti mul’atu keessaa 90–95% qabata.
- Umrii: Baay’inaan waggaa 60–70 gidduutti mul’ata.
- Saala: Dhiira irratti dubartoota caalaa baay’ata (2:1).
- Ilaalcha: Sababa qorannoo fakkii (imaging) babal’ateen, osoo hin yaadamin argamuun isaa dabalaa jira.
- Sigaaraa aarsuu: Sababa hunda caalaa jijjiiramuu danda’u dha.
- Furdaan garmalee (Obesity)
- Dhibee dhiibbaa dhiigaa (Hypertension)
- Dhibee kalee sugaa (CKD): Keessattuu warra dhiqiinsa kalee (dialysis) godhatan.
- Genetic syndromes: Von Hippel-Lindau (VHL), Hereditary papillary RCC.
- Clear Cell RCC (70–80%): Madda: Proximal tubule. Bifa keelloo qaba.
- Papillary RCC (10–15%): Iddoo garaa garaatti fi kalee lamaan irratti mul’ata.
- Chromophobe RCC (5%): Madda: Intercalated cells. Carraa fayyuu gaarii qaba.
Classic Triad:
- Dhiigni fincaan keessatti argamuu (Hematuria)
- Dhukkubbii cinaachaa (Flank pain)
- Itaa harkaan namatti dhaga’amu (Palpable mass)
- CT Scan (Contrast-enhanced) = Gold Standard
- MRI: Yoo hiddni dhiigaa (IVC) qabame.
- Localized: Partial nephrectomy (filatamaa) ykn Radical nephrectomy.
- Advanced: Targeted therapy (VEGF inhibitors) fi Immunotherapy.
- Hubachiisa Kaansariin kun Chemotherapy fi Radiotherapy dhaan hin fayyu.
